Do I need to refrigerate my Gut Probiotic? Julia July 13, 2020 13:49 Updated Follow Refrigerating your Gut Probiotic is not required, but we recommend that you refrigerate your Gut Probiotic. Related articles What are Bonafide Essentials? Is it safe to take multiple Essentials together? Are there interactions? When should I take my Essentials? Do I need to take them with food? Are Bonafide Essentials gluten-free? Are there any side effects associated with Bonafide Essentials? Comments 0 comments Article is closed for comments.